GutConnect 365 Review: United Naturals Supplement for Leaky Gut

If you’ve clicked onto this article you may already be experiencing uncomfortable symptoms like bloating, fatigue, headaches and very inconvenient bowel issues. And you might be wondering if you could be suffering from leaky gut syndrome. Thats where GutConnect 365 comes in.

GutConnect 365 claims to strengthen your gut lining, improve digestion and beat bloating. We’ll be examining the ingredients and the science behind if and why it works so you can make an informed decision about if this product is right for you and your health concerns.

GutConnect 365 At a Glance

Gut connect 365

Our Rating: 4.5/5 star rating liver md

“A quality probiotic supplement for healthy gut lining. Also could assist with bloating”

Top Rated AlternativeGutMD by 1MD


Our Rating: 4.9/5 star rating liver md

“One of the highest rated gut repair supplements in the market. Aims to support gut lining whilst also boosting the immune system” See full review

What is Leaky Gut?

Leaky gut syndrome is a type of digestive condition that refers to the increased permeability of your intestinal lining. When your gut lining is functioning normally, there are tight openings in it that only allow nutrients and water into your bloodstream. 

A leaky gut means that these openings widen to allow toxins, bacteria, food, and other harmful substances to leak out into your bloodstream. This causes an immune response that can result in fatigue, headaches, inflammation, chronic diarrhea, constipation, or bloating, and much more.

Some medical experts believe that leaky gut syndrome does not exist within itself, but is more or a symptom of other diseases rather than the cause. Other experts say that leaky gut can contribute to diabetes, Crohn’s disease, celiac disease, irritable bowel syndrome (IBS), and more – although it is not clear whether it’s a cause or a symptom.

It’s believed that a poor diet that’s high in processed foods and low in fibre, alcohol consumption, certain medications and stress can lead to a leaky gut, but an exact cause is yet to be identified – making it a tricky issue to treat. 

How Gut Connect 365 works

gutconnect 365

GutConnect 365 is a powdered product made by the company United Naturals. It’s a proprietary blend of 9 superfoods (plus natural flavours and Stevia Leaf Extract for sweetness) that aim to nourish and strengthen the gut lining.

If you consume the recommended 1 scoop daily of the vanilla-cinnamon flavoured powder dissolved into water, United Naturals believes you will feel these overall health benefits:

  • Higher energy levels
  • Improved mood
  • Less fatigue
  • Fewer digestive issues
  • Better weight management
  • More restful sleep

United Naturals are based in the USA. They claim to source the best ingredients from around the world and create their products with renewable energy and recyclable materials, ensuring to test all their products to meet a strict quality standard.

Dr. Vincent Pedre, M.D. is the Chief Wellness Officer at United Naturals, taking a holistic approach to medicine after graduating with honours and receiving his degree at the University of Miami School of Medicine.

Active ingredients in GutConnect 365

gutconnect 365 ingredients facts

Now that we know the supposed benefits and a bit more about the company behind GutConnect 365, let’s dive a bit deeper into the ingredients and see if this product can really do anything to improve a leaky gut. We’ve explored each ingredient and also listed the amount that you’ll consume per daily serving of GutConnect 365.

L-Glutamine – 5000mg 

As the most powerful amino acid (building block of proteins) in your body, L-glutamine is probably going to be the most beneficial ingredient in Gut Connect 365 when it comes to repairing and strengthening the intestinal wall. 

Glutamine supplementation has been shown to support gastrointestinal mucosal growth and prevent the mucosal lining from atrophying over time.

It does this by supporting the synthesis of proteins even in times where stress, trauma, and even radiation can have negative effects on the body’s ability to maintain healthy mucosa in the gut lining.

This protein synthesising process promotes healthy cell regeneration, which is essential for a strong gut as the cells in your gut lining renew every 4-5 days

Although further studies are needed to determine the efficacy of glutamine supplementation, it can be concluded that L-Glutamine will assist with improving your gut lining and therefore increase its essential barrier function to improve leaky gut.

Quercetin Dihydrate – 500mg

This ingredient is a long-lasting and powerful antioxidant, which is a substance that inhibits oxidative stress and deterioration in your cells.

Quercetin is also known to stabilise certain cells in your gut that would otherwise increase intestinal permeability. When unstabilised, these cells called ‘mast’ cells actually release histamine – a chemical that causes allergy symptoms

One study suggests that quercetin may even enhance intestinal barrier function within as little as 6 hours after consumption, making it a fast-acting ingredient and a smart addition to this product.

Slippery Elm Bark – 150mg

Ulmus rubra, or slippery elm, is a currently endangered plant that has been used in traditional gastrointestinal medicine for centuries in the United States.

It’s mainly used as an emollient and demulcent to soften and protect the mucous lining of the gut but can be used to also treat hyperacidity and ulcerative conditions due to its inflammatory properties.

Combined with similarly soothing ingredients that relieve irritation like licorice, marshmallow and aloe vera, slippery elm is an excellent ingredient for calming the gut lining.

Organic Marshmallow Root – 150mg

This herb is beneficial to gut health because it has a high mucilage content, meaning that it contains a thick, gluey substance produced by most plants that forms a protective film over mucous membranes, like your gut lining. When it comes into contact with your gut lining, it acts as reinforcement to soothe and strengthen the gut walls with a protective barrier. This function is known to be effective on internal inflammations and irritations such as diarrhea and ulcers. 

There isn’t a lot of research on the exact effects of marshmallow root on gut health but, in theory, there could be some protective benefits that this ingredient provides whilst the gut lining is healing itself through the aid of other ingredients in Gut Connect 365.

N-Acetyl Glucosamine – 150mg

In the gut, N-Acetyl Glucosamine, (NAG) is able to prevent biofilm formation on E.coli – a type of bacteria that can come in some nasty forms and cause diarrhea, cramping and vomiting in extreme cases. Reducing biofilm formation means the bacteria is more susceptible to immune mechanisms and makes it less likely to colonise in the gut and cause issues. 

Generally, though, NAG is a simple sugar found in the shells of crustaceans that’s used mostly for joint pain and stiffness, especially osteoarthritis. One study suggested that NAG might be able to reduce the severity and recurrence inflammatory bowel disease (IBD), showing that it has anti-inflammatory properties that may be useful in the gut. However, there isn’t a lot of research currently available to support or explore it’s true effectiveness definitively. 

Licorice root extract (deglycyrrhizinated) – 150mg

Glycyrrhizin is a compound in licorice that can have adverse effects on human like low potassium levels and muscle weakness when consumed regularly, removing it from the licorice means that it’s safe for consumption – which is why the extract in this product contains deglycyrrhizinated licorice root.

Deglycyrrhizinated licorice may increase mucus production, help treat ulcers and even hepatitis C. It also has antioxidant and anti-inflammatory properties that make it a beneficial addition to this product.

Aloe Vera Extract – 50mg

Aloe vera has long been used and known for its amazing anti-inflammatory properties that help to soothe sunburn, cuts and abrasions. Inside the gut, aloe vera actually supports the mucosal lining, helps to heal ulcers and can help to alleviate constipation by increasing the water content in your gut

A study on IBS sufferers in 2017 showed that aloe vera is a safe and effective treatment to ease symptoms. Aloe vera has also been shown to influence mast cells, similar to Quercetin Dihydrate mentioned above, by decreasing the production of histamines that lead to allergic reactions.

Maitake Mushroom Extract – 30mg

This particular mushroom extract has likely been chosen for this product because of the powerful immune-stimulating properties it possesses. Maitake mushroom extract can also increase fat metabolism for better overall health, exhibits anti-cancer activity and helps to decrease the chances of viral infections.

Maitake mushrooms are rich in antioxidants, vitamins B and C, minerals, fiber, potassium and amino acids – all of which are essential to good gut health.

Zinc Orotate – 20mg


This ingredient is an insoluble organic salt that is bound to orotic acid to increase its metabolism in the body and is generally the most common form of zinc on the supplement market right now.

Zinc is found in the cells of the body working to keep the immune system healthy, it can be naturally found in foods like oysters, red meat, poultry, beans, nuts, whole grains and more.

A zinc deficiency can cause hair loss, loss of appetite or taste, and diarrhea.

For gut health, zinc is able to support the cells in the lining of your gut, increase the effectiveness of Quercetin Dihydrate included in Gut Connect 365 and generally improve leaky gut signs and symptoms.

Having a beneficial and important mineral such as zinc in this supplement will boost its overall effectiveness with helping heal your leaky gut.

Other ingredients

Apart from the main active ingredients discussed above, there are a few extra bits and pieces that we’d like to take a look at as well.

  • Natural Flavors – This supplement has a pleasant vanilla-cinnamon taste that is made possible through the addition of natural flavouring, nothing to worry about unless you personally don’t like the flavour.
  • MCT Oil Powder – Most commonly extracted from coconuts, MCT oil is an easily digested substance that promotes weight loss. In this product its main function is most likely to improve the blendability of the drink.
  • Rebaudioside A (Stevia Leaf Extract) – Generally around 200 times sweeter than white sugar, this type of stevia is used to sweeten the flavour of this supplement. It has almost zero calories and has been shown to have positive effects on both cholesterol and blood sugar levels.

Allergen info – Contains tree nuts and shellfish as per the official ingredients label from the United Naturals website.

Pricing and returns

Keeping in mind that 1 jar will last you a month (1 scoop a day), we’ve listed the prices for buying multiple jars below. If you were to use Gut Connect 365 continuously for a year, it would end up costing you a minimum of $488, which includes United Naturals’ free shipping.

  • 1 jar – $54
  • 3 jars – $134 ($44.66 each)
  • 6 jars – $244 ($40.66 each)

As for returns, if you’re not happy with this product, the company will offer you a refund within 60 days of the date your credit card was charged for the order. You can return 2 empty containers of the same product with any additional jars needing to be still completely sealed.

Returning more than 2 containers will result in a prorated refund for any sealed product. Your shipping costs will not be reimbursed. 

RETURNS SUMMARY: It’s a bit complicated but basically, yes, you can receive a refund if you’re not happy with the results of Gut Connect 365 (minus the return shipping costs). 

Summary of GutConnect 365

This product from United Naturals contains many beneficial and powerful natural ingredients that all seem to have some degree of gut-healing properties. From supporting the mucosal lining to decreasing inflammation and allergic reactions in the body, this product seems as though it would have a wide range of benefits for anyone experiencing leaky gut issues.

When weighing up whether this product is right for you, it’s a good idea to consider costing, refund policies, and customer satisfaction. For a month’s worth of product, this supplement may not be cheap but if it’s the only product you’re using then it might not be too much of a strain on your wallet.

Unfortunately, the only reviews we could find of this product came from those who received a commission for advertising the products and therefore we’re unable to make any conclusions regarding customer satisfaction at this time

If you’re suffering from leaky gut, this product has some awesome ingredients that may help to ease your symptoms. You can try this product risk-free for 60 days with United Naturals refund policy so it may be worth a go to see if this product can help improve your health and quality of life.

Our Recommendation

GutMD – Our Rating: 4.9/5 star rating liver md

You can read our full review of this product here.


About Adele Taylor

Adele is budding content writer from Sydney who's constantly delving into the world of health and fitness in both her professional and personal life to uncover important answers for her readers and herself. She enjoys reading, writing, exercising, and enjoying as many of Sydney's culinary delights as possible.

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  1. Tree nuts and shellfish mixed into this product is absolutely not acceptable!!! Especially for those that have allergens, high blood pressure, diabetes and the like!! So people be forewarned please!! Also this product costs in CADs just too much given the cost of natural wholesome foods as it is. Perhaps it really works and people can afford it thinking we’ll your health is everything. Having said that there are wholesome foods put there that can bring your gut health back in order without the the tree nuts and shellfish. Investigate and learn…it’s ok to treat yourself to a doughnut once a while or whatever. However, it’s not easy, but it doesn’t have to be a chore, …so take the time to learn about foods…


    1. I live in Canada and got 3 jars I took the capsules for 3 months and work good but haven’t started the powder but a bit nervous to do itI am on blood pressure pills and nexium it cost so much money but if it works be good not sure if I should sent it back but it took so long to get here might not return my money I wish I had just ordered capsules


  2. Buying a supplemental tonic is easy. What about the necessary diet restrictions that go with it? No gluten, no soy, etc, etc, etc. is the supplement of any value if you don’t embrace the diet.?


  3. I’m allergic to cinnamon and am disappointed to learn that this a other leaky gut formulas favor cinnamon in their recipe. Sorry, I’m out.


  4. I take medicine for acid reflux can I still take gut connect 365?


    1. Hi Linda, it’s best to consult your doctor before trying anything new.


  5. Well, I am going to complete my first month taking Gut Connect 365 and the truth is that I have not noticed any change for good, on the contrary I feel that I am more inflamed, I feel constipated, and more accumulated gases, I am very disappointed with the product. I would like to get a refund of my money as I feel like I have been scammed with a product that is just misleading marketing.


  6. I am allergic reactions I am allergic to shrimp. I didn’t know this product has shellfish. I bought 3 jars. Shrimp is the only one I cannot have. What do you suggest I do?


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